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Comparison of pharmacokinetic profiles of seven major bioactive components in normal and non-alcoholic fatty liver disease (NAFLD) rats after oral administration of Ling-Gui-Zhu-Gan decoction by UPLC-MS/MS
A sensitive and rapid ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) method was hereby developed for the determination of seven components, namely, glycyrrhizic acid, glycyrrhetinic acid, dehydrotumulosic acid, isoliquiritin, liquiritin, atractylenolide III, and cinnam...
Autores principales: | Nie, Wenlong, Yang, Yang, Li, Ling, Ding, Yue, Chen, Xingmi, Li, Ming, He, Ning, Ji, Guang, Zhang, Yong, Kang, Ping, Zhang, Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192568/ https://www.ncbi.nlm.nih.gov/pubmed/37214449 http://dx.doi.org/10.3389/fphar.2023.1174742 |
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