COVID-19 immune response in adults post Measles-Rubella vaccination

OBJECTIVE: This study aimed to see how measles, mumps, and rubella vaccination affected the increase in SARS-CoV-2 immunoglobulin levels in individuals who had received the second dose of the SARS-CoV-2 vaccine. MATERIAL AND METHOD: This research is a quasi-experimental type with a pre-post test des...

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Detalles Bibliográficos
Autores principales: Suwoyo, Suwoyo, Yani, Erna Rahma, Hardjito, Koekoeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier España, S.L.U. 2023
Materias:
Special Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192594/
https://www.ncbi.nlm.nih.gov/pubmed/37362839
http://dx.doi.org/10.1016/j.vacun.2023.05.004
Descripción
Sumario:OBJECTIVE: This study aimed to see how measles, mumps, and rubella vaccination affected the increase in SARS-CoV-2 immunoglobulin levels in individuals who had received the second dose of the SARS-CoV-2 vaccine. MATERIAL AND METHOD: This research is a quasi-experimental type with a pre-post test design. The population studied were adults who had received the second dose of the SARS-CoV-2 vaccine, consisting of 30 people. RESULTS: The results of this study were that most (60%) research subjects experienced an increase in IgM and some subjects (46.6%) experienced an increase in anti-SARS-CoV-2 IgG levels. The administration of the MR vaccination had no effect on increasing anti-SARS-CoV-2 IgG and IgM levels. This happened because the increase in IgM and IgG levels in the pre and post-tests in most research subjects was relatively low. CONCLUSION: The administration of the MR vaccine to adults who had received a second dose of the SARS-CoV-2 vaccine elicited a response with low levels of IgG and IgM SARS-CoV-2.

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