Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features

Intracranial germ cell tumors (iGCTs) are uncommon brain tumors that mainly occur in children. Differing in histology, location, and gender of the patients, iGCTs are often divided into germinomas and non-germinomatous germ cell tumors (NGGCTs). Early diagnosis and timely treatment are crucial to iG...

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Autores principales: Yang, Mingwen, Wang, Jian, Zhang, Lin, Liu, Jungang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192609/
https://www.ncbi.nlm.nih.gov/pubmed/37215600
http://dx.doi.org/10.3389/fped.2023.1141397
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author Yang, Mingwen
Wang, Jian
Zhang, Lin
Liu, Jungang
author_facet Yang, Mingwen
Wang, Jian
Zhang, Lin
Liu, Jungang
author_sort Yang, Mingwen
collection PubMed
description Intracranial germ cell tumors (iGCTs) are uncommon brain tumors that mainly occur in children. Differing in histology, location, and gender of the patients, iGCTs are often divided into germinomas and non-germinomatous germ cell tumors (NGGCTs). Early diagnosis and timely treatment are crucial to iGCTs, the subtypes of which have substantial variations. This review summarized the clinical and radiological features of iGCTs at different sites, and reviewed the recent advances in neuroimaging of iGCTs, which can help predict tumor subtypes early and guide clinical decision-making.
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spelling pubmed-101926092023-05-19 Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features Yang, Mingwen Wang, Jian Zhang, Lin Liu, Jungang Front Pediatr Pediatrics Intracranial germ cell tumors (iGCTs) are uncommon brain tumors that mainly occur in children. Differing in histology, location, and gender of the patients, iGCTs are often divided into germinomas and non-germinomatous germ cell tumors (NGGCTs). Early diagnosis and timely treatment are crucial to iGCTs, the subtypes of which have substantial variations. This review summarized the clinical and radiological features of iGCTs at different sites, and reviewed the recent advances in neuroimaging of iGCTs, which can help predict tumor subtypes early and guide clinical decision-making. Frontiers Media S.A. 2023-05-04 /pmc/articles/PMC10192609/ /pubmed/37215600 http://dx.doi.org/10.3389/fped.2023.1141397 Text en © 2023 Yang, Wang, Zhang and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Yang, Mingwen
Wang, Jian
Zhang, Lin
Liu, Jungang
Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features
title Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features
title_full Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features
title_fullStr Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features
title_full_unstemmed Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features
title_short Update on MRI in pediatric intracranial germ cell tumors—The clinical and radiological features
title_sort update on mri in pediatric intracranial germ cell tumors—the clinical and radiological features
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192609/
https://www.ncbi.nlm.nih.gov/pubmed/37215600
http://dx.doi.org/10.3389/fped.2023.1141397
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AT zhanglin updateonmriinpediatricintracranialgermcelltumorstheclinicalandradiologicalfeatures
AT liujungang updateonmriinpediatricintracranialgermcelltumorstheclinicalandradiologicalfeatures

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