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Distinct synaptic pools of DAPK1 differentially regulate activity-dependent synaptic CaMKII accumulation

The death-associated protein kinase 1 (DAPK1) regulates the synaptic movement of the Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII). Synaptic CaMKII accumulation is mediated via binding to the NMDA-receptor subunit GluN2B and is required for long-term potentiation (LTP). By contrast, l...

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Detalles Bibliográficos
Autores principales: Tullis, Jonathan E., Bayer, K. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192646/
https://www.ncbi.nlm.nih.gov/pubmed/37216104
http://dx.doi.org/10.1016/j.isci.2023.106723