Single-cell transcriptomics reveals heterogeneity and intercellular crosstalk in human intervertebral disc degeneration

The complexity of the human intervertebral disc (IVD) has hindered the elucidation of the microenvironment and mechanisms underlying IVD degeneration (IVDD). Here we determined the landscapes of nucleus pulposus (NP), annulus fibrosus (AF), and immunocytes in human IVD by scRNA-seq. Six NP subcluste...

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Detalles Bibliográficos
Autores principales: Wang, Dandan, Li, ZiZhang, Huang, Weimin, Cao, Shengnan, Xie, Liangyu, Chen, Yuanzhen, Li, Huazhong, Wang, Lei, Chen, Xiaoshu, Yang, Jian-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192848/
https://www.ncbi.nlm.nih.gov/pubmed/37216089
http://dx.doi.org/10.1016/j.isci.2023.106692

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