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Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature
Synovial sarcoma is a mesenchymal spindle cell tumor. Primary pancreatic sarcomas are extremely rare. The present study describes a rare case of synovial sarcoma in the head of the pancreas. A 35-year-old male presented with left upper quadrant abdominal pain. An endoscopic ultrasound examination re...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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D.A. Spandidos
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192948/ https://www.ncbi.nlm.nih.gov/pubmed/37214230 http://dx.doi.org/10.3892/mi.2023.82 |
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author | Ali, Rebaz M. Seerwan, Karzan Ali, Shano M. Abdullah, Ari M. Hawrami, Omar Hussein, Dlsoz M. Mohammed, Bruj Jamil Karim, Muhammad Abdullah, Fakher Abdalla, Berun A. Kakamad, Fahmi H. |
author_facet | Ali, Rebaz M. Seerwan, Karzan Ali, Shano M. Abdullah, Ari M. Hawrami, Omar Hussein, Dlsoz M. Mohammed, Bruj Jamil Karim, Muhammad Abdullah, Fakher Abdalla, Berun A. Kakamad, Fahmi H. |
author_sort | Ali, Rebaz M. |
collection | PubMed |
description | Synovial sarcoma is a mesenchymal spindle cell tumor. Primary pancreatic sarcomas are extremely rare. The present study describes a rare case of synovial sarcoma in the head of the pancreas. A 35-year-old male presented with left upper quadrant abdominal pain. An endoscopic ultrasound examination revealed a complex solid-cystic lesion in the pancreatic head. He had undergone pancreaticoduodenectomy (Whipple procedure). A histological examination yielded negative results for AE1/AE3, CD10, S100, CD34, desmin, smooth muscle actin, β-catenin, CD117, HMB45, chromogranin and synaptophysin. However, the results were positive for TLEI and vimentin, which is consistent with synovial sarcoma. Synovial sarcoma is a soft tissue malignant tumor. Primary pancreatic sarcomas frequently present as large, high-grade tumors in the pancreatic head. Histologically, there are several types of synovial sarcoma, such as monophasic, biphasic and poorly differentiated. A histological examination is necessary for the diagnosis as the imaging findings are not specifically suggestive of synovial sarcoma. The preferred course of treatment is complete resection with wide margins, followed by adjuvant chemotherapy and/or radiotherapy. Primary mesenchymal tumors of the pancreas are extremely uncommon. As a result, a diagnosis requires careful evaluation. Surgical resection is the main modality of treatment. |
format | Online Article Text |
id | pubmed-10192948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-101929482023-05-19 Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature Ali, Rebaz M. Seerwan, Karzan Ali, Shano M. Abdullah, Ari M. Hawrami, Omar Hussein, Dlsoz M. Mohammed, Bruj Jamil Karim, Muhammad Abdullah, Fakher Abdalla, Berun A. Kakamad, Fahmi H. Med Int (Lond) Case Report Synovial sarcoma is a mesenchymal spindle cell tumor. Primary pancreatic sarcomas are extremely rare. The present study describes a rare case of synovial sarcoma in the head of the pancreas. A 35-year-old male presented with left upper quadrant abdominal pain. An endoscopic ultrasound examination revealed a complex solid-cystic lesion in the pancreatic head. He had undergone pancreaticoduodenectomy (Whipple procedure). A histological examination yielded negative results for AE1/AE3, CD10, S100, CD34, desmin, smooth muscle actin, β-catenin, CD117, HMB45, chromogranin and synaptophysin. However, the results were positive for TLEI and vimentin, which is consistent with synovial sarcoma. Synovial sarcoma is a soft tissue malignant tumor. Primary pancreatic sarcomas frequently present as large, high-grade tumors in the pancreatic head. Histologically, there are several types of synovial sarcoma, such as monophasic, biphasic and poorly differentiated. A histological examination is necessary for the diagnosis as the imaging findings are not specifically suggestive of synovial sarcoma. The preferred course of treatment is complete resection with wide margins, followed by adjuvant chemotherapy and/or radiotherapy. Primary mesenchymal tumors of the pancreas are extremely uncommon. As a result, a diagnosis requires careful evaluation. Surgical resection is the main modality of treatment. D.A. Spandidos 2023-03-24 /pmc/articles/PMC10192948/ /pubmed/37214230 http://dx.doi.org/10.3892/mi.2023.82 Text en Copyright: © Ali et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Ali, Rebaz M. Seerwan, Karzan Ali, Shano M. Abdullah, Ari M. Hawrami, Omar Hussein, Dlsoz M. Mohammed, Bruj Jamil Karim, Muhammad Abdullah, Fakher Abdalla, Berun A. Kakamad, Fahmi H. Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature |
title | Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature |
title_full | Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature |
title_fullStr | Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature |
title_full_unstemmed | Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature |
title_short | Primary pancreatic synovial sarcoma: Report of a rare case and review of the literature |
title_sort | primary pancreatic synovial sarcoma: report of a rare case and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10192948/ https://www.ncbi.nlm.nih.gov/pubmed/37214230 http://dx.doi.org/10.3892/mi.2023.82 |
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