Neonatal and adult cardiac fibroblasts exhibit inherent differences in cardiac regenerative capacity

Directly reprogramming fibroblasts into cardiomyocytes improves cardiac function in the infarcted heart. However, the low efficacy of this approach hinders clinical applications. Unlike the adult mammalian heart, the neonatal heart has an intrinsic regenerative capacity. Consequently, we hypothesize...

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Detalles Bibliográficos
Autores principales: Sun, Hualing, Pratt, Richard E., Dzau, Victor J., Hodgkinson, Conrad P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193010/
https://www.ncbi.nlm.nih.gov/pubmed/37044217
http://dx.doi.org/10.1016/j.jbc.2023.104694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193010/
https://www.ncbi.nlm.nih.gov/pubmed/37044217
http://dx.doi.org/10.1016/j.jbc.2023.104694

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