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Neonatal and adult cardiac fibroblasts exhibit inherent differences in cardiac regenerative capacity
Directly reprogramming fibroblasts into cardiomyocytes improves cardiac function in the infarcted heart. However, the low efficacy of this approach hinders clinical applications. Unlike the adult mammalian heart, the neonatal heart has an intrinsic regenerative capacity. Consequently, we hypothesize...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193010/ https://www.ncbi.nlm.nih.gov/pubmed/37044217 http://dx.doi.org/10.1016/j.jbc.2023.104694 |