Nasal administration of recombinant Neospora caninum secreting IL-15/IL-15Rα inhibits metastatic melanoma development in lung

BACKGROUND: Metastases are the leading cause of mortality in many cancer types and lungs are one of the most common sites of metastasis alongside the liver, brain, and bones. In melanoma, 85% of late-stage patients harbor lung metastases. A local administration could enhance the targeting of metasta...

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Detalles Bibliográficos
Autores principales: Battistoni, Arthur, Lantier, Louis, di Tommaso, Anne, Ducournau, Céline, Lajoie, Laurie, Samimi, Mahtab, Coënon, Loïs, Rivière, Clément, Epardaud, Mathieu, Hertereau, Leslie, Poupée-Beaugé, Agathe, Rieu, Juliette, Mévélec, Marie-Noëlle, Lee, Gordon Scott, Moiré, Nathalie, Germon, Stephanie, Dimier-Poisson, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193056/
https://www.ncbi.nlm.nih.gov/pubmed/37192784
http://dx.doi.org/10.1136/jitc-2023-006683

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