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Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis

BACKGROUND: Immunosuppressive tumor microenvironment (ITM) remains an obstacle that jeopardizes clinical immunotherapy. METHODS: To address this concern, we have engineered an exosome inherited from M1-pheototype macrophages, which thereby retain functions and ingredients of the parent M1-phenotype...

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Detalles Bibliográficos
Autores principales:	Wang, Duo, Qiu, Guanhua, Zhu, Xiaoqi, Wang, Qin, Zhu, Chunyan, Fang, Chao, Liu, Junjie, Zhang, Kun, Liu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Oncolytic and Local Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193064/ https://www.ncbi.nlm.nih.gov/pubmed/37192783 http://dx.doi.org/10.1136/jitc-2022-006516

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