OCT4 induces long-lived dedifferentiated kidney progenitors poised to redifferentiate in 3D kidney spheroids

Upscaling of kidney epithelial cells is crucial for renal regenerative medicine. Nonetheless, the adult kidney lacks a distinct stem cell hierarchy, limiting the ability to long-term propagate clonal populations of primary cells that retain renal identity. Toward this goal, we tested the paradigm of...

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Detalles Bibliográficos
Autores principales: Omer, Dorit, Zontag, Osnat Cohen, Gnatek, Yehudit, Harari-Steinberg, Orit, Pleniceanu, Oren, Namestnikov, Michael, Cohen, Ayelet-Hashahar, Nissim-Rafinia, Malka, Tam, Gal, Kalisky, Tomer, Meshorer, Eran, Dekel, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193171/
https://www.ncbi.nlm.nih.gov/pubmed/37214315
http://dx.doi.org/10.1016/j.omtm.2023.04.005

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