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Relationship between hepatic and mitochondrial ceramides: a novel in vivo method to track ceramide synthesis

Ceramides (CERs) are key intermediate sphingolipids implicated in contributing to mitochondrial dysfunction and the development of multiple metabolic conditions. Despite the growing evidence of CER role in disease risk, kinetic methods to measure CER turnover are lacking, particularly using in vivo...

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Detalles Bibliográficos
Autores principales: Mucinski, Justine M., McCaffrey, Jonas M., Rector, R. Scott, Kasumov, Takhar, Parks, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193228/
https://www.ncbi.nlm.nih.gov/pubmed/37028768
http://dx.doi.org/10.1016/j.jlr.2023.100366