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Relationship between hepatic and mitochondrial ceramides: a novel in vivo method to track ceramide synthesis
Ceramides (CERs) are key intermediate sphingolipids implicated in contributing to mitochondrial dysfunction and the development of multiple metabolic conditions. Despite the growing evidence of CER role in disease risk, kinetic methods to measure CER turnover are lacking, particularly using in vivo...
Autores principales: | Mucinski, Justine M., McCaffrey, Jonas M., Rector, R. Scott, Kasumov, Takhar, Parks, Elizabeth J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193228/ https://www.ncbi.nlm.nih.gov/pubmed/37028768 http://dx.doi.org/10.1016/j.jlr.2023.100366 |
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