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Conserved regions of the regulatory subunit Spo7 are required for Nem1–Spo7/Pah1 phosphatase cascade function in yeast lipid synthesis

In the yeast Saccharomyces cerevisiae, the Nem1–Spo7 complex is a protein phosphatase that activates Pah1 phosphatidate phosphatase at the nuclear–endoplasmic reticulum membrane for the synthesis of triacylglycerol. The Nem1–Spo7/Pah1 phosphatase cascade largely controls whether phosphatidate is par...

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Detalles Bibliográficos
Autores principales: Jog, Ruta, Han, Gil-Soo, Carman, George M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193233/
https://www.ncbi.nlm.nih.gov/pubmed/37030502
http://dx.doi.org/10.1016/j.jbc.2023.104683