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eIF2α incites photoreceptor cell and retina damage by all-trans-retinal

Dry age-related macular degeneration (AMD) and recessive Stargardt’s disease (STGD1) lead to irreversible blindness in humans. The accumulation of all-trans-retinal (atRAL) induced by chaos in visual cycle is closely associated with retinal atrophy in dry AMD and STGD1 but its critical downstream si...

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Detalles Bibliográficos
Autores principales:	He, Danxue, Tao, Lei, Cai, Binxiang, Chen, Xiangjun, Wang, Yan, Li, Shiying, Liao, Chunyan, Chen, Yuling, Chen, Jingmeng, Liu, Zuguo, Wu, Yalin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193240/ https://www.ncbi.nlm.nih.gov/pubmed/37031820 http://dx.doi.org/10.1016/j.jbc.2023.104686

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