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Revealing the immune cell subtype reconstitution profile in patients from the CLARITY study using deconvolution algorithms after cladribine tablets treatment
Immune Cell Deconvolution methods utilizing gene expression profiling to quantify immune cells in tissues and blood are an appealing alternative to flow cytometry. Our objective was to investigate the applicability of deconvolution approaches in clinical trial settings to better investigate the mode...
Autores principales: | Kalatskaya, Irina, Giovannoni, Gavin, Leist, Thomas, Cerra, Joseph, Boschert, Ursula, Rolfe, P. Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193326/ https://www.ncbi.nlm.nih.gov/pubmed/37202447 http://dx.doi.org/10.1038/s41598-023-34384-5 |
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