New Synthesis of Diarylmethanes, Key Building Blocks for SGLT2 Inhibitors

[Image: see text] Synthesis of diarylmethanes, a key building block for SGLT2 inhibitors, has been developed through ketone synthesis by Friedel–Crafts acylation with TiCl(4), followed by reduction with TiCl(4)/NaBH(4). The new protocol proceeded more cleanly than the previous methods employing AlCl...

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Detalles Bibliográficos
Autores principales: Seki, Masahiko, Tapkir, Sandeep Ramesharao, Nadiveedhi, Maheshwara Reddy, Mulani, Shaheen Kasim, Mashima, Kazushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193421/
https://www.ncbi.nlm.nih.gov/pubmed/37214716
http://dx.doi.org/10.1021/acsomega.3c01972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193421/
https://www.ncbi.nlm.nih.gov/pubmed/37214716
http://dx.doi.org/10.1021/acsomega.3c01972

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