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New Synthesis of Diarylmethanes, Key Building Blocks for SGLT2 Inhibitors

[Image: see text] Synthesis of diarylmethanes, a key building block for SGLT2 inhibitors, has been developed through ketone synthesis by Friedel–Crafts acylation with TiCl(4), followed by reduction with TiCl(4)/NaBH(4). The new protocol proceeded more cleanly than the previous methods employing AlCl...

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Detalles Bibliográficos
Autores principales:	Seki, Masahiko, Tapkir, Sandeep Ramesharao, Nadiveedhi, Maheshwara Reddy, Mulani, Shaheen Kasim, Mashima, Kazushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193421/ https://www.ncbi.nlm.nih.gov/pubmed/37214716 http://dx.doi.org/10.1021/acsomega.3c01972

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