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Regiocontrolled Synthesis of 1-Substituted-3(5)-carboxyalkyl-1H-pyrazoles Using Trichloromethyl Enones

[Image: see text] In this work, we present a regiocontrolled methodology to prepare 1-substituted-3(5)-carboxyalkyl-1H-pyrazoles using trichloromethyl enones as starting materials. It was found that the selectivity of the reaction depends on the nature of the hydrazine: when using arylhydrazine hydr...

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Detalles Bibliográficos
Autores principales: Pereira, Genilson S., Mittersteiner, Mateus, Bonacorso, Helio G., Martins, Marcos A. P., Zanatta, Nilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193424/
https://www.ncbi.nlm.nih.gov/pubmed/37214703
http://dx.doi.org/10.1021/acsomega.3c01879

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