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Room-Temperature, Copper-Free, and Amine-Free Sonogashira Reaction in a Green Solvent: Synthesis of Tetraalkynylated Anthracenes and In Vitro Assessment of Their Cytotoxic Potentials
[Image: see text] The multifold Sonogashira coupling of a class of aryl halides with arylacetylene in the presence of an equivalent of Cs(2)CO(3) has been accomplished using a combination of Pd(CH(3)CN)(2)Cl(2) (0.5 mol %) and cataCXium A (1 mol %) under copper-free and amine-free conditions in a re...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193572/ https://www.ncbi.nlm.nih.gov/pubmed/37214732 http://dx.doi.org/10.1021/acsomega.3c00732 |