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Multidrug resistant 1 (MDR1) C3435T and G2677T gene polymorphism: impact on the risk of acute rejection in pediatric kidney transplant recipients

BACKGROUND: Tacrolimus is the backbone drug in kidney transplantation. Single nucleotide polymorphism of Multidrug resistant 1 gene can affect tacrolimus metabolism consequently it can affect tacrolimus trough level and incidence of acute rejection. The aim of this study is to investigate the impact...

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Detalles Bibliográficos
Autores principales: Korkor, Mai S, el-desoky, Tarek, Mosaad, Youssef M, Salah, Doaa M., Hammad, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193607/
https://www.ncbi.nlm.nih.gov/pubmed/37198710
http://dx.doi.org/10.1186/s13052-023-01469-w