Effervescent cannabidiol solid dispersion-doped dissolving microneedles for boosted melanoma therapy via the “TRPV1-NFATc1-ATF3” pathway and tumor microenvironment engineering

BACKGROUND: Conventional dissolving microneedles (DMNs) face significant challenges in anti-melanoma therapy due to the lack of active thrust to achieve efficient transdermal drug delivery and intra-tumoral penetration. METHODS: In this study, the effervescent cannabidiol solid dispersion-doped diss...

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Detalles Bibliográficos
Autores principales: Shi, Jiachen, Ma, Qiuling, Su, Wenting, Liu, Congyan, Zhang, Huangqin, Liu, Yuping, Li, Xiaoqi, Jiang, Xi, Ge, Chang, Kong, Fei, Chen, Yan, Qu, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193696/
https://www.ncbi.nlm.nih.gov/pubmed/37198657
http://dx.doi.org/10.1186/s40824-023-00390-x

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