Cargando…

Exploring the role of pyroptosis in shaping the tumor microenvironment of colorectal cancer by bulk and single-cell RNA sequencing

BACKGROUND: Emerging studies have shown that pyroptosis plays a non-negligible role in the development and treatment of tumors. However, the mechanism of pyroptosis in colorectal cancer (CRC) remains still unclear. Therefore, this study investigated the role of pyroptosis in CRC. METHODS: A pyroptos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Chengsheng, Yang, Xiao, Li, Shuchun, Zhang, Enkui, Fan, Xiaodong, Huang, Ling, He, Zirui, Sun, Jing, Ma, Junjun, Zang, Lu, Zheng, Minhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193704/ https://www.ncbi.nlm.nih.gov/pubmed/37198617 http://dx.doi.org/10.1186/s12935-023-02897-8

Ejemplares similares

Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer
por: Zhang, Enkui, et al.
Publicado: (2023)

Exploring the relationship between lactate metabolism and immunological function in colorectal cancer through genes identification and analysis
por: Zhang, Enkui, et al.
Publicado: (2023)

Roles and mechanisms of tumour-infiltrating B cells in human cancer: a new force in immunotherapy
por: Zhang, Enkui, et al.
Publicado: (2023)

Impact of Cuproptosis-related markers on clinical status, tumor immune microenvironment and immunotherapy in colorectal cancer: A multi-omic analysis
por: Shao, Yanfei, et al.
Publicado: (2023)

Significant clinical response of advanced colorectal cancer to combination therapy involving capecitabine and adoptive cell transfer therapy: a case report
por: Li, Shuchun, et al.
Publicado: (2019)

Comprehensive exploration of tumor immune microenvironment feature and therapeutic response in colorectal cancer based on a novel immune-related long non-coding RNA prognostic signature
por: Zhou, Xueliang, et al.
Publicado: (2022)

PSMC5 Promotes Proliferation and Metastasis of Colorectal Cancer by Activating Epithelial–Mesenchymal Transition Signaling and Modulating Immune Infiltrating Cells
por: He, Zirui, et al.
Publicado: (2021)

An intravenous anesthetic drug-propofol, influences the biological characteristics of malignant tumors and reshapes the tumor microenvironment: A narrative literature review
por: Zhou, Xueliang, et al.
Publicado: (2022)

GJA1 is a Prognostic Biomarker and Correlated with Immune Infiltrates in Colorectal Cancer
por: Hu, Wenjun, et al.
Publicado: (2020)

Pyroptosis, metabolism, and tumor immune microenvironment
por: Du, Tiantian, et al.
Publicado: (2021)

ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy inmetastatic colorectal cancer: ACACB is a biomarker for CTX therapy in metastatic CRC
por: Hong, Hi-Ju, et al.
Publicado: (2022)

Integrated single-cell and bulk RNA sequencing analysis identified pyroptosis-related signature for diagnosis and prognosis in osteoarthritis
por: Chen, Yanzhong, et al.
Publicado: (2023)

The role of pyroptosis in modulating the tumor immune microenvironment
por: Wu, Jinxiang, et al.
Publicado: (2022)

Microsatellite Status Affects Tumor Response and Survival in Patients Undergoing Neoadjuvant Chemotherapy for Clinical Stage III Gastric Cancer
por: Cai, Zhenghao, et al.
Publicado: (2020)

NDRG1 enhances the sensitivity of cetuximab by modulating EGFR trafficking in colorectal cancer
por: Yang, Guang, et al.
Publicado: (2021)

N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21
por: Zhang, Sen, et al.
Publicado: (2019)

Single-cell and bulk tissue sequencing unravels the heterogeneity of synovial microenvironment in arthrofibrosis
por: Chen, Xi, et al.
Publicado: (2023)

Integrated analysis of single-cell and bulk RNA sequencing data reveals an immunostimulatory microenvironment in tumor thrombus of osteosarcoma
por: Ji, Tao, et al.
Publicado: (2023)

Pyroptosis-Related Gene to Construct Prognostic Signature and Explore Immune Microenvironment and Immunotherapy Biomarkers in Bladder Cancer
por: Zhang, Xiangyu, et al.
Publicado: (2022)

A greater lymph node yield is required during pathological examination in microsatellite instability-high gastric cancer
por: Cai, Zhenghao, et al.
Publicado: (2021)

Prolonged neoadjuvant chemotherapy without radiation versus total neoadjuvant therapy for locally advanced rectal cancer: A propensity score matched study
por: Zhao, Xuan, et al.
Publicado: (2022)

Pyroptosis related genes signature predicts prognosis and immune infiltration of tumor microenvironment in hepatocellular carcinoma
por: Fang, Guoxu, et al.
Publicado: (2022)

Classification of pyroptosis patterns and construction of a novel prognostic model for prostate cancer based on bulk and single-cell RNA sequencing
por: Fu, Jianhan, et al.
Publicado: (2022)

Clinical-mediated discovery of pyroptosis in CD8(+) T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence
por: Zhang, Ying, et al.
Publicado: (2023)

Identification of pyroptosis-related subtypes, the development of a prognosis model, and characterization of tumor microenvironment infiltration in colorectal cancer
por: Song, Wei, et al.
Publicado: (2021)

Research Progress on the Role of Pyroptosis in Myocardial Ischemia-Reperfusion Injury
por: Liu, Yang, et al.
Publicado: (2022)

Comprehensive analysis of pyroptosis regulators and tumor immune microenvironment in clear cell renal cell carcinoma
por: Zhang, Yan, et al.
Publicado: (2021)

A Pyroptosis-Based Prognostic Model for Immune Microenvironment Estimation of Hepatocellular Carcinoma
por: Chen, Zhihong, et al.
Publicado: (2022)

Microenvironment‐Responsive Prodrug‐Induced Pyroptosis Boosts Cancer Immunotherapy
por: Xiao, Yao, et al.
Publicado: (2021)

Pyroptosis Patterns Are Involved in Immune Microenvironment Regulation of Dilated Cardiomyopathy
por: Wang, Kexin, et al.
Publicado: (2022)

A pyroptosis-related gene signature predicts prognosis and immune microenvironment in hepatocellular carcinoma
por: Jin, Yifeng, et al.
Publicado: (2022)

Integrating Bulk Transcriptome and Single-Cell RNA Sequencing Data Reveals the Landscape of the Immune Microenvironment in Thoracic Aortic Aneurysms
por: Wang, Qunhui, et al.
Publicado: (2022)

Apoptin induces pyroptosis of colorectal cancer cells via the GSDME-dependent pathway
por: Liu, Zirui, et al.
Publicado: (2022)

Integrative analysis revealed that distinct cuprotosis patterns reshaped tumor microenvironment and responses to immunotherapy of colorectal cancer
por: Xu, Ximo, et al.
Publicado: (2023)

A Pyroptosis-Related Gene Panel for Predicting the Prognosis and Immune Microenvironment of Cervical Cancer
por: Hu, Haoran, et al.
Publicado: (2022)

Prognostic Value of a Pyroptosis-Related Long Noncoding RNA Signature Associated with Osteosarcoma Microenvironment
por: Bu, Xinxin, et al.
Publicado: (2021)

The Metastasis Suppressor, N-myc Downregulated Gene 1 (NDRG1), Is a Prognostic Biomarker for Human Colorectal Cancer
por: Mao, Zhihai, et al.
Publicado: (2013)

Tumor Microenvironment Shapes Colorectal Cancer Progression, Metastasis, and Treatment Responses
por: Li, Jun, et al.
Publicado: (2022)

Infrapyloric (No. 206) and greater curvature (No. 204) lymph node metastasis in adenocarcinoma located in the right half of the transverse colon (InCLART Study): protocol for a multicentre prospective observational study
por: Yalikun, Abudushalamu, et al.
Publicado: (2023)

Combining bulk RNA-sequencing and single-cell RNA-sequencing data to reveal the immune microenvironment and metabolic pattern of osteosarcoma
por: Huang, Ruichao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3eevnc209k6fm5oc3dh7lmd6gr