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Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy

OBJECTIVES: The aim of the study was to determine whether left ventricular electrical potential measured by electromechanical mapping with the NOGA XP system has predictive value for response to CRT. BACKGROUND: Approximately 30% of patients who undergo cardiac resynchronization therapy do not see t...

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Autores principales: Wilczek, Jacek, Jadczyk, Tomasz, Wojakowski, Wojciech, Gołba, Krzysztof S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193837/
https://www.ncbi.nlm.nih.gov/pubmed/37215549
http://dx.doi.org/10.3389/fcvm.2023.1107415
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author Wilczek, Jacek
Jadczyk, Tomasz
Wojakowski, Wojciech
Gołba, Krzysztof S.
author_facet Wilczek, Jacek
Jadczyk, Tomasz
Wojakowski, Wojciech
Gołba, Krzysztof S.
author_sort Wilczek, Jacek
collection PubMed
description OBJECTIVES: The aim of the study was to determine whether left ventricular electrical potential measured by electromechanical mapping with the NOGA XP system has predictive value for response to CRT. BACKGROUND: Approximately 30% of patients who undergo cardiac resynchronization therapy do not see the expected effects. METHODS: The group of 38 patients qualified for CRT implantation were included in the study, of which 33 patients were analyzed. A 15% reduction in ESV after 6 months of pacing was used as a criterion for a positive response to CRT. The mean value and sum of unipolar and bipolar potentials obtained by mapping with the NOGA XP system and their predictive value in relation to the effect of CRT were analyzed using a bulls-eye projection at three levels: 1) the global value of the left ventricular (LV) potentials, 2) the potentials of the individual LV walls and 3) the mean value of the potentials of the individual segments (basal and middle) of the individual LV walls. RESULTS: 24 patients met the criterion of a positive response to CRT vs. 9 non-responders. At the global analysis stage, the independent predictors of favorable response to CRT were the sum of the unipolar potential and bipolar mean potential. In the analysis of individual left ventricular walls, the mean bipolar potential of the anterior and posterior wall and in the unipolar system, mean septal potential was found to be an independent predictor of favorable response to CRT. In the detailed segmental analysis, the independent predictors were the bipolar potential of the mid-posterior wall segment and the basal anterior wall segment. CONCLUSIONS: Measurement of bipolar and unipolar electrical potentials with the NOGA XP system is a valuable method for predicting a favorable response to CRT.
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spelling pubmed-101938372023-05-19 Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy Wilczek, Jacek Jadczyk, Tomasz Wojakowski, Wojciech Gołba, Krzysztof S. Front Cardiovasc Med Cardiovascular Medicine OBJECTIVES: The aim of the study was to determine whether left ventricular electrical potential measured by electromechanical mapping with the NOGA XP system has predictive value for response to CRT. BACKGROUND: Approximately 30% of patients who undergo cardiac resynchronization therapy do not see the expected effects. METHODS: The group of 38 patients qualified for CRT implantation were included in the study, of which 33 patients were analyzed. A 15% reduction in ESV after 6 months of pacing was used as a criterion for a positive response to CRT. The mean value and sum of unipolar and bipolar potentials obtained by mapping with the NOGA XP system and their predictive value in relation to the effect of CRT were analyzed using a bulls-eye projection at three levels: 1) the global value of the left ventricular (LV) potentials, 2) the potentials of the individual LV walls and 3) the mean value of the potentials of the individual segments (basal and middle) of the individual LV walls. RESULTS: 24 patients met the criterion of a positive response to CRT vs. 9 non-responders. At the global analysis stage, the independent predictors of favorable response to CRT were the sum of the unipolar potential and bipolar mean potential. In the analysis of individual left ventricular walls, the mean bipolar potential of the anterior and posterior wall and in the unipolar system, mean septal potential was found to be an independent predictor of favorable response to CRT. In the detailed segmental analysis, the independent predictors were the bipolar potential of the mid-posterior wall segment and the basal anterior wall segment. CONCLUSIONS: Measurement of bipolar and unipolar electrical potentials with the NOGA XP system is a valuable method for predicting a favorable response to CRT. Frontiers Media S.A. 2023-05-04 /pmc/articles/PMC10193837/ /pubmed/37215549 http://dx.doi.org/10.3389/fcvm.2023.1107415 Text en © 2023 Wilczek, Jadczyk, Wojakowski and Gołba. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Wilczek, Jacek
Jadczyk, Tomasz
Wojakowski, Wojciech
Gołba, Krzysztof S.
Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
title Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
title_full Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
title_fullStr Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
title_full_unstemmed Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
title_short Left ventricular electrical potential measured by the NOGA XP electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
title_sort left ventricular electrical potential measured by the noga xp electromechanical mapping method as a predictor of response to cardiac resynchronization therapy
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193837/
https://www.ncbi.nlm.nih.gov/pubmed/37215549
http://dx.doi.org/10.3389/fcvm.2023.1107415
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