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METTL3 affects FLT3-ITD+ acute myeloid leukemia by mediating autophagy by regulating PSMA3-AS1 stability

The study was designed to explore the role of PSMA3-AS1 in initiation and progression of acute myeloid leukemia (AML) and investigate its action mechanism. Expression of PSMA3-AS1, miR-20a-5p and ATG16L1 both in vitro and in vivo was measured by qRT-PCR. The expression of protein was detected by wes...

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Detalles Bibliográficos
Autores principales: Wu, Shenghao, Weng, Shanshan, Zhou, Wenjin, Chen, Yuemiao, Liu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193868/
https://www.ncbi.nlm.nih.gov/pubmed/37088992
http://dx.doi.org/10.1080/15384101.2023.2204770

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