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Non-canonical helical transitions and conformational switching are associated with characteristic flexibility and disorder indices in TRP and Kv channels

Structural evidence and much experimental data have demonstrated the presence of non-canonical helical substructures (π and 3(10)) in regions of great functional relevance both in TRP as in Kv channels. Through an exhaustive compositional analysis of the sequences underlying these substructures, we...

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Detalles Bibliográficos
Autores principales: García-Morales, Abigail, Balleza, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193913/
https://www.ncbi.nlm.nih.gov/pubmed/37196183
http://dx.doi.org/10.1080/19336950.2023.2212349