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Non-canonical helical transitions and conformational switching are associated with characteristic flexibility and disorder indices in TRP and Kv channels
Structural evidence and much experimental data have demonstrated the presence of non-canonical helical substructures (π and 3(10)) in regions of great functional relevance both in TRP as in Kv channels. Through an exhaustive compositional analysis of the sequences underlying these substructures, we...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193913/ https://www.ncbi.nlm.nih.gov/pubmed/37196183 http://dx.doi.org/10.1080/19336950.2023.2212349 |