Antithetic effects of agonists and antagonists on the structural fluctuations of TRPV1 channel

Transient receptor potential vanilloid member 1 (TRPV1) is a heat and capsaicin receptor that allows cations to permeate and cause pain. As the molecular basis for temperature sensing, the heat capacity (ΔC(p)) model [D. E. Clapham, C. Miller, Proc. Natl. Acad. Sci. U.S.A. 108, 19492–19497 (2011).]...

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Detalles Bibliográficos
Autores principales: Sumino, Ayumi, Zhao, Yimeng, Mukai, Daichi, Sumikama, Takashi, Puppulin, Leonardo, Hattori, Motoyuki, Shibata, Mikihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193963/
https://www.ncbi.nlm.nih.gov/pubmed/37155841
http://dx.doi.org/10.1073/pnas.2301013120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193963/
https://www.ncbi.nlm.nih.gov/pubmed/37155841
http://dx.doi.org/10.1073/pnas.2301013120

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