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The Chlamydia trachomatis type III-secreted effector protein CteG induces centrosome amplification through interactions with centrin-2

The centrosome is the main microtubule organizing center of the cell and is crucial for mitotic spindle assembly, chromosome segregation, and cell division. Centrosome duplication is tightly controlled, yet several pathogens, most notably oncogenic viruses, perturb this process leading to increased...

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Detalles Bibliográficos
Autores principales: Steiert, Brianna, Icardi, Carolina M., Faris, Robert, McCaslin, Paige N., Smith, Parker, Klingelhutz, Aloysius J., Yau, Peter M., Weber, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193975/
https://www.ncbi.nlm.nih.gov/pubmed/37155906
http://dx.doi.org/10.1073/pnas.2303487120