Epstein–Barr virus LMP1 protein promotes proliferation and inhibits differentiation of epithelial cells via activation of YAP and TAZ

Latent Epstein–Barr virus (EBV) infection promotes undifferentiated nasopharyngeal carcinomas (NPCs) in humans, but the mechanism(s) for this effect has been difficult to study because EBV cannot transform normal epithelial cells in vitro and the EBV genome is often lost when NPC cells are grown in...

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Detalles Bibliográficos
Autores principales: Singh, Deo R., Nelson, Scott E., Pawelski, Abigail S., Kansra, Alisha S., Fogarty, Stuart A., Bristol, Jillian A., Ohashi, Makoto, Johannsen, Eric C., Kenney, Shannon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193989/
https://www.ncbi.nlm.nih.gov/pubmed/37155846
http://dx.doi.org/10.1073/pnas.2219755120

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