Syndecan-4 is a maestro of gastric cancer cell invasion and communication that underscores poor survival

Gastric cancer is a dominating cause of cancer-associated mortality with limited therapeutic options. Here, we show that syndecan-4 (SDC4), a transmembrane proteoglycan, is highly expressed in intestinal subtype gastric tumors and that this signature associates with patient poor survival. Further, w...

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Detalles Bibliográficos
Autores principales: Poças, Juliana, Marques, Catarina, Gomes, Catarina, Otake, Andreia Hanada, Pinto, Filipe, Ferreira, Mariana, Silva, Tiago, Faria-Ramos, Isabel, Matos, Rita, Ribeiro, Ana Raquel, Senra, Emanuel, Cavadas, Bruno, Batista, Sílvia, Maia, Joana, Macedo, Joana A., Lima, Luís, Afonso, Luís Pedro, Ferreira, José Alexandre, Santos, Lúcio Lara, Polónia, António, Osório, Hugo, Belting, Mattias, Reis, Celso A., Costa-Silva, Bruno, Magalhães, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10193992/
https://www.ncbi.nlm.nih.gov/pubmed/37155874
http://dx.doi.org/10.1073/pnas.2214853120

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