ALKBH4 Stabilization Is Required for Arsenic-Induced 6mA DNA Methylation Inhibition, Keratinocyte Malignant Transformation, and Tumorigenicity

Inorganic arsenic is one of the well-known human skin carcinogens. However, the molecular mechanism by which arsenic promotes carcinogenesis remains unclear. Previous studies have established that epigenetic changes, including changes in DNA methylation, are among the critical mechanisms that drive...

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Detalles Bibliográficos
Autores principales: Cui, Yan-Hong, Wilkinson, Emma, Peterson, Jack, He, Yu-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194016/
https://www.ncbi.nlm.nih.gov/pubmed/37207134
http://dx.doi.org/10.3390/w14223595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194016/
https://www.ncbi.nlm.nih.gov/pubmed/37207134
http://dx.doi.org/10.3390/w14223595

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