In a zebrafish biomedical model of human Allan-Herndon-Dudley syndrome impaired MTH signaling leads to decreased neural cell diversity

BACKGROUND: Maternally derived thyroid hormone (T3) is a fundamental factor for vertebrate neurodevelopment. In humans, mutations on the thyroid hormones (TH) exclusive transporter monocarboxylic acid transporter 8 (MCT8) lead to the Allan-Herndon-Dudley syndrome (AHDS). Patients with AHDS present s...

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Detalles Bibliográficos
Autores principales: Silva, Nádia, Campinho, Marco António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194031/
https://www.ncbi.nlm.nih.gov/pubmed/37214246
http://dx.doi.org/10.3389/fendo.2023.1157685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194031/
https://www.ncbi.nlm.nih.gov/pubmed/37214246
http://dx.doi.org/10.3389/fendo.2023.1157685

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