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White-matter abnormalities and cognitive dysfunction are linked to astrocyte activation in sickle mice
White-matter injury in sickle-cell disease (SCD) includes silent cerebral infarction diagnosed by diffusion tensor imaging (DTI), a complication associated with cognitive dysfunction in children with SCD. The link between white-matter injury and cognitive dysfunction has not been fully elucidated. T...
Autores principales: | Hazra, Rimi, Pu, Hongjian, Foley, Lesley M, Little-Ihrig, Lynda, Hitchens, T Kevin, Ghosh, Samit, Ofori-Acquah, Solomon F, Hu, Xiaoming, Novelli, Enrico M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194090/ https://www.ncbi.nlm.nih.gov/pubmed/37215630 http://dx.doi.org/10.1093/pnasnexus/pgad149 |
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