Cargando…

Lessons from resistance analysis in clinical trials of IV zanamivir

Influenza infection causes substantial morbidity and mortality during seasonal epidemics and pandemics. Antivirals, including neuraminidase inhibitors, play an important role in the treatment of severely ill patients infected with influenza. Resistance is a key factor that can affect the efficacy of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yates, Phillip J, Mehta, Nalini, Watson, Helen A, Peppercorn, Amanda F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194138/ https://www.ncbi.nlm.nih.gov/pubmed/36610656 http://dx.doi.org/10.1016/j.virusres.2023.199039

Ejemplares similares

Population Pharmacokinetic/Pharmacodynamic Analysis of Intravenous Zanamivir in Healthy Adults and Hospitalized Adult and Pediatric Subjects With Influenza
por: Zuo, Peiying, et al.
Publicado: (2019)

Zanamivir aqueous solution in severe influenza: A global Compassionate Use Program, 2009–2019
por: Wang‐Jairaj, Jie, et al.
Publicado: (2021)

Safety and Pharmacokinetics of Intravenous Zanamivir Treatment in Hospitalized Adults With Influenza: An Open-label, Multicenter, Single-Arm, Phase II Study
por: Marty, Francisco M., et al.
Publicado: (2014)

Zanamivir should be inhaled, not nebulised
por: Eagel, Barry A
Publicado: (2010)

Intravenous zanamivir for influenza myocarditis and enteral malabsorption
por: Jahns, Fritz-Patrick, et al.
Publicado: (2018)

Zanamivir versus trivalent split virus influenza vaccine: a pilot randomized trial
por: Coleman, Brenda L, et al.
Publicado: (2015)

1062 Compassionate Use of Intravenous (IV) Zanamivir During the 2013-2014 Influenza Season: Case Series of Three Patients
por: Shah, Punit, et al.
Publicado: (2014)

Neuraminidase Inhibitor Zanamivir Ameliorates Collagen-Induced Arthritis
por: Sehnert, Bettina, et al.
Publicado: (2021)

Oseltamivir-Resistant Pandemic (H1N1) 2009 Treated with Nebulized Zanamivir
por: Da Dalt, Liviana, et al.
Publicado: (2010)

Exploring the Mechanism of Zanamivir Resistance in a Neuraminidase Mutant: A Molecular Dynamics Study
por: Han, Nanyu, et al.
Publicado: (2012)

Successful Treatment of Complicated Influenza A(H3N2) Virus Infection and Rhabdomyolysis with Compassionate Use of IV Zanamivir
por: Alchikh, Maren, et al.
Publicado: (2023)

Study of Oseltamivir and Zanamivir Resistance-Related Mutations in Influenza Viruses Isolated from Wild Mallards in Sweden
por: Orozovic, Goran, et al.
Publicado: (2014)

Zanamivir Oral Delivery: Enhanced Plasma and Lung Bioavailability in Rats
por: Shanmugam, Srinivasan, et al.
Publicado: (2013)

Comparison of efficacy and safety of oseltamivir and zanamivir in pandemic influenza treatment
por: Tuna, Nazan, et al.
Publicado: (2012)

Detection of Resistance Mutations to Antivirals Oseltamivir and Zanamivir in Avian Influenza A Viruses Isolated from Wild Birds
por: Orozovic, Goran, et al.
Publicado: (2011)

Zanamivir for the prevention of influenza in adults and children age 5 years and older
por: Eiland, Lea S, et al.
Publicado: (2007)

Zanamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments
por: Heneghan, Carl J, et al.
Publicado: (2014)

A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir
por: Abed, Yacine, et al.
Publicado: (2017)

Efficacy of Oseltamivir-Zanamivir Combination Compared to Each Monotherapy for Seasonal Influenza: A Randomized Placebo-Controlled Trial
por: Duval, Xavier, et al.
Publicado: (2010)

Efficacy of oseltamivir compared with zanamivir in COPD patients with seasonal influenza virus infection: a randomized controlled trial
por: Li, Min, et al.
Publicado: (2020)

Development of oseltamivir and zanamivir resistance in influenza A(H1N1)pdm09 virus, Denmark, 2014
por: Trebbien, Ramona, et al.
Publicado: (2017)

Molecular modeling and lead design of substituted zanamivir derivatives as potent anti-influenza drugs
por: Dholakia, Dhwani, et al.
Publicado: (2016)

Correction: Efficacy of Oseltamivir-Zanamivir Combination Compared to Each Monotherapy for Seasonal Influenza: A Randomized Placebo-Controlled Trial
por: Duval, Xavier, et al.
Publicado: (2010)

A two-year survey of the oseltamivir-resistant influenza A(H1N1) virus in Yamagata, Japan and the clinical effectiveness of oseltamivir and zanamivir
por: Matsuzaki, Yoko, et al.
Publicado: (2010)

The Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine Model
por: Morokutti-Kurz, Martina, et al.
Publicado: (2015)

Permeability Enhancers Dramatically Increase Zanamivir Absolute Bioavailability in Rats: Implications for an Orally Bioavailable Influenza Treatment
por: Holmes, Eric H., et al.
Publicado: (2013)

Comparison of the clinical effectiveness of zanamivir and laninamivir octanoate for children with influenza A(H3N2) and B in the 2011–2012 season
por: Koseki, Naoko, et al.
Publicado: (2014)

IF-03 Clinical Effectiveness of Oseltamivir or Zanamivir for Influenza A/H1N1 Virus with or without H274Y Mutation
por: Kawai, Naoki, et al.
Publicado: (2009)

A Validated HPLC Method for Zanamivir and its Application to In vitro Permeability Study in Caco-2 Culture Model
por: Boonyapiwat, B., et al.
Publicado: (2011)

Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks
por: Anekthananon, T., et al.
Publicado: (2013)

Oseltamivir and inhaled zanamivir as influenza prophylaxis in Thai health workers: a randomized, double-blind, placebo-controlled safety trial over 16 weeks
por: Anekthananon, T., et al.
Publicado: (2013)

Characteristics and mortality of severe influenza cases treated with parenteral aqueous zanamivir, United Kingdom, October 2009 to January 2011
por: Cleary, Paul Robert, et al.
Publicado: (2018)

Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?
por: Yu, Kunqian, et al.
Publicado: (2009)

Oseltamivir/zanamivir: Lack of efficacy leading to fatal influenza A (H1N1) infection: case report
Publicado: (2013)

In Silico Studies Reveal Peramivir and Zanamivir as an Optimal Drug Treatment Even If H7N9 Avian Type Influenza Virus Acquires Further Resistance
por: Sarukhanyan, Edita, et al.
Publicado: (2022)

Prone position ventilation, recruitment maneuver and intravenous zanamivir in severe refractory hypoxemia caused by influenza A (H1N1)
por: Biatto, Jair F P, et al.
Publicado: (2010)

Clinical outcomes of patients treated with intravenous zanamivir for severe influenza A(H1N1)pdm09 infection: a case report series
por: Torti, Carlo, et al.
Publicado: (2019)

Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir
por: Meijer, Wouter J., et al.
Publicado: (2015)

Alloferon and Zanamivir Show Effective Antiviral Activity against Influenza A Virus (H1N1) Infection In Vitro and In Vivo
por: Lee, Dahae, et al.
Publicado: (2022)

Evaluation of the Antiviral Response to Zanamivir Administered Intravenously for Treatment of Critically Ill Patients With Pandemic Influenza A (H1N1) Infection
por: Fraaij, P. L. A., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_8nidmrm55dh6cc9rudeqgd35hn