Imidazonaphthyridine effects on Chikungunya virus replication: Antiviral activity by dependent and independent of interferon type 1 pathways

The Chikungunya virus (CHIKV) causes Chikungunya fever, a disease characterized by symptoms such as arthralgia/polyarthralgia. Currently, there are no antivirals approved against CHIKV, emphasizing the need to develop novel therapies. The imidazonaphthyridine compound (RO8191), an interferon-α (IFN-...

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Detalles Bibliográficos
Autores principales: Ruiz, Uriel Enrique Aquino, Santos, Igor Andrade, Grosche, Victória Riquena, Fernandes, Rafaela Sachetto, de Godoy, Andre Schutzer, Torres, Jhoan David Aguillón, Freire, Marjorie Caroline Liberato Cavalcanti, Mesquita, Nathalya Cristina de Moraes Roso, Guevara-Vega, Marco, Nicolau-Junior, Nilson, Sabino-Silva, Robinson, Mineo, Tiago Wilson Patriarca, Oliva, Glaucius, Jardim, Ana Carolina Gomes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194360/
https://www.ncbi.nlm.nih.gov/pubmed/36565816
http://dx.doi.org/10.1016/j.virusres.2022.199029

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