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Case report: A combined immunotherapy strategy as a promising therapy for MSI-H colorectal carcinomas with multiple HPD risk factors

Approximately 5% of advanced colorectal carcinomas (CRCs) and 12–15% of early CRCs are microsatellite instability-high (MSI-H) or mismatch repair-deficient (dMMR) tumors. Nowadays, PD-L1 inhibitors or combined CTLA4 inhibitors are the major strategies for advanced or metastatic MSI-H colorectal canc...

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Detalles Bibliográficos
Autores principales: Zhang, Jinli, Yang, Lu, Kong, Fanwei, Wu, Di, Hu, Baoru, Yang, Jie, He, Jiaxin, Liu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194834/
https://www.ncbi.nlm.nih.gov/pubmed/37215717
http://dx.doi.org/10.3389/fmed.2023.1051034