Identification of some bioactive compounds from Trignonella foenumgraecum as possible inhibitors of PPAR(ϒ) for diabetes treatment through molecular docking studies, pharmacophore modelling and ADMET profiling: An in-silico study

Oral antidiabetic agents including the peroxisome proliferator-activated receptor gamma (PPARγ) agonists are available for the clinical management of diabetes mellitus (DM) but most are characterized by many adverse effects. In this study, we explore the antidiabetic properties of phytoconstituents...

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Detalles Bibliográficos
Autores principales: Okoh, Olayinka Sunday, Yakubu, AbdulbasitHaliru, Adegboyega, Abayomi Emmanuel, Uti, Daniel Ejim, Obeten, Uket Nta, Agada, Samuel Ali, Oluwaloni, Folusho, Johnson, Grace Inioluwa, Mela, Leonard Paul, Asomadu, Rita Onyekachukwu, Iwaloye, Opeyemi, Johnson, Titilayo Omolara, Orji, Obasi Uche.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194899/
https://www.ncbi.nlm.nih.gov/pubmed/37200359
http://dx.doi.org/10.1371/journal.pone.0284210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194899/
https://www.ncbi.nlm.nih.gov/pubmed/37200359
http://dx.doi.org/10.1371/journal.pone.0284210

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