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COVID-19 in patients with paracoccidioidomycosis
INTRODUCTION: In 2020, we reported the first patient with concomitant COVID-19 and paracoccidioidomycosis (PCM). Since then, no other cases have been recorded in the literature. We aim to update information on the occurrence of COVID-19 in patients with PCM followed at a reference center for infecti...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194906/ https://www.ncbi.nlm.nih.gov/pubmed/37155708 http://dx.doi.org/10.1371/journal.pntd.0011322 |
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author | de Macedo, Priscila Marques Benko, Lorena Macedo Pestana Falcão, Eduardo Mastrangelo Marinho Nosanchuk, Joshua D. Almeida-Paes, Rodrigo do Valle, Antonio Carlos Francesconi |
author_facet | de Macedo, Priscila Marques Benko, Lorena Macedo Pestana Falcão, Eduardo Mastrangelo Marinho Nosanchuk, Joshua D. Almeida-Paes, Rodrigo do Valle, Antonio Carlos Francesconi |
author_sort | de Macedo, Priscila Marques |
collection | PubMed |
description | INTRODUCTION: In 2020, we reported the first patient with concomitant COVID-19 and paracoccidioidomycosis (PCM). Since then, no other cases have been recorded in the literature. We aim to update information on the occurrence of COVID-19 in patients with PCM followed at a reference center for infectious diseases at Rio de Janeiro, Brazil. METHODS: We reviewed the medical records from patients diagnosed with PCM who presented with clinical symptoms, radiological findings, and/or laboratory diagnosis of COVID-19 at any time during their acute or follow-up care. The clinical profiles of these patients were described. RESULTS: Between March 2020 and September 2022, we identified six individuals with COVID-19 among the 117 patients with PCM evaluated. The median age was 38 years and the male to female ratio 2:1. Most patients (n = 5) presented for evaluation due to acute PCM. The severity of COVID-19 ranged from mild to severe in acute PCM and only the single patient with chronic PCM died. CONCLUSIONS: There is a range of disease severity in COVID-19 and PCM co-infection and concomitant disease may represent a severe association, especially in the chronic type of the mycosis with pulmonary involvement. As COVID-19 and chronic PCM share similar clinical aspects and PCM is neglected, it is probable that COVID-19 has been hampering simultaneous PCM diagnosis, which can explain the absence of new co-infection reports. With the continued persistence of COVID-19 globally, these findings further suggest that more attention by providers is necessary to identify co-infections with Paracoccidioides. |
format | Online Article Text |
id | pubmed-10194906 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-101949062023-05-19 COVID-19 in patients with paracoccidioidomycosis de Macedo, Priscila Marques Benko, Lorena Macedo Pestana Falcão, Eduardo Mastrangelo Marinho Nosanchuk, Joshua D. Almeida-Paes, Rodrigo do Valle, Antonio Carlos Francesconi PLoS Negl Trop Dis Research Article INTRODUCTION: In 2020, we reported the first patient with concomitant COVID-19 and paracoccidioidomycosis (PCM). Since then, no other cases have been recorded in the literature. We aim to update information on the occurrence of COVID-19 in patients with PCM followed at a reference center for infectious diseases at Rio de Janeiro, Brazil. METHODS: We reviewed the medical records from patients diagnosed with PCM who presented with clinical symptoms, radiological findings, and/or laboratory diagnosis of COVID-19 at any time during their acute or follow-up care. The clinical profiles of these patients were described. RESULTS: Between March 2020 and September 2022, we identified six individuals with COVID-19 among the 117 patients with PCM evaluated. The median age was 38 years and the male to female ratio 2:1. Most patients (n = 5) presented for evaluation due to acute PCM. The severity of COVID-19 ranged from mild to severe in acute PCM and only the single patient with chronic PCM died. CONCLUSIONS: There is a range of disease severity in COVID-19 and PCM co-infection and concomitant disease may represent a severe association, especially in the chronic type of the mycosis with pulmonary involvement. As COVID-19 and chronic PCM share similar clinical aspects and PCM is neglected, it is probable that COVID-19 has been hampering simultaneous PCM diagnosis, which can explain the absence of new co-infection reports. With the continued persistence of COVID-19 globally, these findings further suggest that more attention by providers is necessary to identify co-infections with Paracoccidioides. Public Library of Science 2023-05-08 /pmc/articles/PMC10194906/ /pubmed/37155708 http://dx.doi.org/10.1371/journal.pntd.0011322 Text en © 2023 de Macedo et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article de Macedo, Priscila Marques Benko, Lorena Macedo Pestana Falcão, Eduardo Mastrangelo Marinho Nosanchuk, Joshua D. Almeida-Paes, Rodrigo do Valle, Antonio Carlos Francesconi COVID-19 in patients with paracoccidioidomycosis |
title | COVID-19 in patients with paracoccidioidomycosis |
title_full | COVID-19 in patients with paracoccidioidomycosis |
title_fullStr | COVID-19 in patients with paracoccidioidomycosis |
title_full_unstemmed | COVID-19 in patients with paracoccidioidomycosis |
title_short | COVID-19 in patients with paracoccidioidomycosis |
title_sort | covid-19 in patients with paracoccidioidomycosis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10194906/ https://www.ncbi.nlm.nih.gov/pubmed/37155708 http://dx.doi.org/10.1371/journal.pntd.0011322 |
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