Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma: Effects of glutathione on Charcot-Leyden crystals and Gal-10

Charcot-Leyden crystals (CLCs) are the hallmark of many eosinophilic-based diseases, such as asthma. Here, we report that reduced glutathione (GSH) disrupts CLCs and inhibits crystallization of human galectin-10 (Gal-10). GSH has no effect on CLCs from monkeys ( Macaca fascicularis or M. mulatta), e...

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Detalles Bibliográficos
Autores principales: Na, Heya, Sayed, Hend, Ayala, Gabriela Jaramillo, Wang, Xing, Liu, Yuhan, Yu, Jinyi, Liu, Tianhao, Mayo, Kevin H., Su, Jiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195141/
https://www.ncbi.nlm.nih.gov/pubmed/36988350
http://dx.doi.org/10.3724/abbs.2023050

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