RNF8 depletion attenuates hepatocellular carcinoma progression by inhibiting epithelial-mesenchymal transition and enhancing drug sensitivity: The role of RNF8 in EMT and drug sensitivity in HCC

Despite substantial advances that have been made in understanding the etiology of hepatocellular carcinoma (HCC), the early-stage diagnosis and treatment of advanced-stage HCC remain a major challenge. RNF8, an E3 ligase important for the DNA damage response, has been proven to facilitate the progre...

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Detalles Bibliográficos
Autores principales: Kuang, Jingyu, Duan, Ting, Gao, Changsong, Liu, Chuanyang, Chen, Si, Zhu, Lv-yun, Min, Lu, Lu, Chenyu, Wang, Wenlun, Zhu, Lingyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195149/
https://www.ncbi.nlm.nih.gov/pubmed/37154586
http://dx.doi.org/10.3724/abbs.2023076

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