Cargando…

Anti-Amyloid Monoclonal Antibodies are Transformative Treatments that Redefine Alzheimer's Disease Therapeutics

Two anti-amyloid monoclonal antibodies (MABs)—lecanemab (Leqembi(®)) and aducanumab (Aduhelm(®))—have been approved in the USA for the treatment of Alzheimer's disease (AD). Anti-amyloid monoclonal antibodies are the first disease-modifying therapies for AD that achieve slowing of clinical decl...

Descripción completa

Detalles Bibliográficos
Autor principal:	Cummings, Jeffrey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Current Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195708/ https://www.ncbi.nlm.nih.gov/pubmed/37060386 http://dx.doi.org/10.1007/s40265-023-01858-9

Ejemplares similares

Trends in the Development and Approval of Monoclonal Antibodies for Viral Infections
por: Reichert, Janice M.
Publicado: (2012)

Clinical and Regulatory Challenges and Opportunities for Monoclonal Antibodies in Low- and Middle-Income Countries: Lessons from COVID-19 and Beyond
por: Gieber, Lisa, et al.
Publicado: (2023)

Therapeutic Potential of Direct Clearance of the Amyloid-β in Alzheimer’s Disease
por: Kim, Dong Eun, et al.
Publicado: (2020)

Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer’s disease
por: Bateman, Randall J., et al.
Publicado: (2022)

Embedding Patient-Centricity by Collaborating with Patients to Transform the Rare Disease Ecosystem
por: Sharma, Rohita, et al.
Publicado: (2023)

Regulatory and Health Technology Assessment Considerations for Disease-Modifying Drugs in Alzheimer’s Disease
por: Bouvy, Jacoline C., et al.
Publicado: (2018)

Amyloid Cascade Hypothesis for the Treatment of Alzheimer’s Disease: Progress and Challenges
por: Wu, Tong, et al.
Publicado: (2022)

Anti-Amyloid-β Monoclonal Antibodies for Alzheimer’s Disease: Pitfalls and Promise
por: van Dyck, Christopher H.
Publicado: (2017)

Novel strategies for Alzheimer's disease treatment: An overview of anti-amyloid beta monoclonal antibodies
por: Rygiel, Katarzyna
Publicado: (2016)

Amyloid-Lowering Monoclonal Antibodies for the Treatment of Early Alzheimer’s Disease
por: Leisher, Solana, et al.
Publicado: (2023)

Improved Therapeutic Approaches are Needed to Manage Graft-versus-Host Disease
por: Hooker, Deborah S., et al.
Publicado: (2021)

Redefining the structure of structured reporting in radiology
por: Nobel, J. Martijn, et al.
Publicado: (2020)

Medical Affairs Transformation in Specialty Pharma: Next-Level Collaboration at the Core
por: Fulford-Smith, Antony, et al.
Publicado: (2022)

Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution
por: Land, Walter Gottlieb
Publicado: (2020)

Preparing for the Next Normal: Transformation in the Role of Medical Affairs Following the COVID-19 Pandemic
por: Ghosh, Romik, et al.
Publicado: (2021)

Digital Transformation in Medical Affairs Sparked by the Pandemic: Insights and Learnings from COVID-19 Era and Beyond
por: Furtner, Daniel, et al.
Publicado: (2021)

How a Bottom-Up Multi-Stakeholder Initiative Helped Transform the Renal Replacement Therapy Landscape in Spain
por: Selgas, Rafael, et al.
Publicado: (2017)

The Future of Antisense Oligonucleotides in the Treatment of Respiratory Diseases
por: Ulanova, Marina, et al.
Publicado: (2012)

Editorial: A Time of Transition of Alzheimer's Disease in the Advent of Anti-Amyloid Monoclonal Antibodies
por: Tousi, Babak, et al.
Publicado: (2021)

Can Anti–β-amyloid Monoclonal Antibodies Work in Autosomal Dominant Alzheimer Disease?
por: Imbimbo, Bruno P., et al.
Publicado: (2020)

Holobiont–Holobiont Interactions: Redefining Host–Parasite Interactions
por: Dheilly, Nolwenn Marie
Publicado: (2014)

Therapeutic Potential of Transdermal Glyceryl Trinitrate in the Management of Acute Stroke
por: Appleton, Jason P., et al.
Publicado: (2016)

The Significance of the Intestinal Microbiome for Vaccinology: From Correlations to Therapeutic Applications
por: Harris, Vanessa C.
Publicado: (2018)

Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel
por: Borén, Jan, et al.
Publicado: (2020)

Biologic Treatment Algorithms for Moderate-to-Severe Psoriasis with Comorbid Conditions and Special Populations: A Review
por: Thatiparthi, Akshitha, et al.
Publicado: (2021)

MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-19
por: Hum, Christine, et al.
Publicado: (2021)

Cardiovascular Risk with Non-steroidal Anti-inflammatory Drugs: Clinical Implications
por: Bello, Alfonso E., et al.
Publicado: (2014)

Redefining the Immune System as a Social Interface for Cooperative Processes
por: Muraille, Eric
Publicado: (2013)

Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current Evidence
por: Facente, Shelley N., et al.
Publicado: (2021)

The Cross-Talk between Age, Hypertension and Inflammation in COVID-19 Patients: Therapeutic Targets
por: Casucci, Gerardo, et al.
Publicado: (2020)

Redefining Medicine's Relationship With the Media in the Era of COVID-19
por: Carlo, Andrew D., et al.
Publicado: (2021)

Redefining the BH3 Death Domain as a ‘Short Linear Motif’
por: Aouacheria, Abdel, et al.
Publicado: (2015)

Calmodulin and Amyloid Beta as Coregulators of Critical Events during the Onset and Progression of Alzheimer’s Disease
por: O’Day, Danton H.
Publicado: (2023)

Basic Considerations for the Use of Monoclonal Antibodies in Migraine
por: Levin, Morris, et al.
Publicado: (2018)

Profound reductions in first and total cardiovascular events with icosapent ethyl in the REDUCE-IT trial: why these results usher in a new era in dyslipidaemia therapeutics
por: Boden, William E, et al.
Publicado: (2020)

Prevention and Treatment of Monkeypox
por: Rizk, John G., et al.
Publicado: (2022)

Role of monoclonal antibody drugs in the treatment of COVID-19
por: Ucciferri, Claudio, et al.
Publicado: (2020)

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association–European Society of Cardiology
por: Maack, Christoph, et al.
Publicado: (2018)

The Place of Cannabinoids in the Treatment of Gynecological Pain
por: Sinclair, Justin, et al.
Publicado: (2023)

Novel Strategies for the Treatment of COVID-19
por: McCarthy, Matthew W.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4qtg35g6jju23dj88n8f6nj036