Cargando…

Recombinant measles virus vaccine rMV-Hu191 exerts an oncolytic effect on esophageal squamous cell carcinoma via caspase-3/GSDME-mediated pyroptosis

Oncolytic viruses have recently been proven to be an effective and promising cancer therapeutic strategy, but there is rare data about oncolytic therapy in esophageal squamous cell carcinoma (ESCC), especially oncolytic measles virotherapy. Therefore, this study aimed to explore whether the recombin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Ailing, Li, Zhongyue, Wang, Yilong, Chen, Yi, Peng, Jinkai, Zhu, Mengying, Li, Yueyue, Song, Hai, Zhou, Dongming, Zhang, Chudi, Lv, Yao, Zhao, Zhengyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195838/ https://www.ncbi.nlm.nih.gov/pubmed/37202386 http://dx.doi.org/10.1038/s41420-023-01466-2

Ejemplares similares

Synergistic antitumor efficacy of rMV-Hu191 and Olaparib in pancreatic cancer by generating oxidative DNA damage and ROS-dependent apoptosis
por: Zhang, Chu-di, et al.
Publicado: (2023)

Synergism of rMV-Hu191 with cisplatin to treat gastric cancer by acid sphingomyelinase-mediated apoptosis requiring integrity of lipid raft microdomains
por: Lv, Yao, et al.
Publicado: (2021)

A recombinant Chinese measles virus vaccine strain rMV-Hu191 inhibits human colorectal cancer growth through inducing autophagy and apoptosis regulating by PI3K/AKT pathway
por: Zhang, Chu-di, et al.
Publicado: (2021)

Enhancement of safety and immunogenicity of the Chinese Hu191 measles virus vaccine by alteration of the S-adenosylmethionine (SAM) binding site in the large polymerase protein
por: Wang, Yilong, et al.
Publicado: (2018)

Immune response elicited in the tumor microenvironment upon rMV‐SLAMblind cancer virotherapy
por: Moritoh, Kanako, et al.
Publicado: (2023)

Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy
por: Li, Wen, et al.
Publicado: (2021)

GSDME-dependent pyroptosis signaling pathway in diabetic nephropathy
por: Li, Shengyu, et al.
Publicado: (2023)

Apoptin induces pyroptosis of colorectal cancer cells via the GSDME-dependent pathway
por: Liu, Zirui, et al.
Publicado: (2022)

GSDME maintains hematopoietic stem cells by balancing pyroptosis and apoptosis
por: Yang, Xiuxiu, et al.
Publicado: (2020)

GSDME maintains hematopoietic stem cells by balancing pyroptosis and apoptosis
Publicado: (2022)

GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis
por: Wei, Yuanyuan, et al.
Publicado: (2023)

Epithelial-Mesenchymal Transition Induces GSDME Transcriptional Activation for Inflammatory Pyroptosis
por: Jia, Chenqiang, et al.
Publicado: (2021)

GSDME Increases Chemotherapeutic Drug Sensitivity by Inducing Pyroptosis in Retinoblastoma Cells
por: Li, Fang, et al.
Publicado: (2022)

Myricetin activates the Caspase-3/GSDME pathway via ER stress induction of pyroptosis in lung cancer cells
por: Han, Jicheng, et al.
Publicado: (2022)

Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity
por: Shen, Xiujin, et al.
Publicado: (2021)

Characterization of GSDME in amphioxus provides insights into the functional evolution of GSDM-mediated pyroptosis
por: Wang, Xinli, et al.
Publicado: (2023)

Antitumor Virotherapy by Attenuated Measles Virus (MV)
por: Guillerme, Jean-Baptiste, et al.
Publicado: (2013)

Cleavage of GSDME by caspase-3 determines lobaplatin-induced pyroptosis in colon cancer cells
por: Yu, Junhui, et al.
Publicado: (2019)

The caspase-3/GSDME signal pathway as a switch between apoptosis and pyroptosis in cancer
por: Jiang, Mingxia, et al.
Publicado: (2020)

BIX‐01294 enhanced chemotherapy effect in gastric cancer by inducing GSDME‐mediated pyroptosis
por: Deng, Bei‐Bei, et al.
Publicado: (2020)

Miltirone induces cell death in hepatocellular carcinoma cell through GSDME-dependent pyroptosis
por: Zhang, Xiaowei, et al.
Publicado: (2020)

A Novel Mechanism of Cannabidiol in Suppressing Hepatocellular Carcinoma by Inducing GSDME Dependent Pyroptosis
por: Shangguan, Fugen, et al.
Publicado: (2021)

Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells
por: Yan, Liang, et al.
Publicado: (2021)

Zika virus causes placental pyroptosis and associated adverse fetal outcomes by activating GSDME
por: Zhao, Zikai, et al.
Publicado: (2022)

OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis
por: Di, Muping, et al.
Publicado: (2022)

Antileukemic effect of venetoclax and hypomethylating agents via caspase-3/GSDME-mediated pyroptosis
por: Ye, Fanghua, et al.
Publicado: (2023)

Preclinical safety assessment of MV-s-NAP, a novel oncolytic measles virus strain armed with an H.pylori immunostimulatory bacterial transgene
por: Viker, Kimberly B., et al.
Publicado: (2022)

BECN1 modulates hematopoietic stem cells by targeting Caspase-3-GSDME-mediated pyroptosis
Publicado: (2022)

BECN1 modulates hematopoietic stem cells by targeting Caspase-3-GSDME-mediated pyroptosis
por: Yang, Xiuxiu, et al.
Publicado: (2020)

Campylobacter jejuni Cytolethal Distending Toxin Induces GSDME-Dependent Pyroptosis in Colonic Epithelial Cells
por: Gu, Jiayun, et al.
Publicado: (2022)

TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis
por: Wu, Jingying, et al.
Publicado: (2023)

CC-115 Mediates GSDME-Dependent Pyroptosis in Lung Adenocarcinoma Through the Akt/Bax Pathway
por: Zhang, Ting, et al.
Publicado: (2023)

Measles to the Rescue: A Review of Oncolytic Measles Virus
por: Aref, Sarah, et al.
Publicado: (2016)

Measles Virus as an Oncolytic Immunotherapy
por: Engeland, Christine E., et al.
Publicado: (2021)

Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate
por: Hu, Lei, et al.
Publicado: (2020)

CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma
por: Rioja-Blanco, Elisa, et al.
Publicado: (2022)

Antitumor Effect of Simvastatin in Combination With DNA Methyltransferase Inhibitor on Gastric Cancer via GSDME-Mediated Pyroptosis
por: Xia, Ying, et al.
Publicado: (2022)

Blocking GSDME-mediated pyroptosis in renal tubular epithelial cells alleviates disease activity in lupus mice
por: Luo, Guihu, et al.
Publicado: (2022)

Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma
por: Chen, Xinyi, et al.
Publicado: (2023)

Measles virus: Background and oncolytic virotherapy
por: Bhattacharjee, Sankhajit, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_v3k7q200u66m3lk71tv57dbork