Harringtonine: A more effective antagonist for Omicron variant

Fusion with host cell membrane is the main mechanism of infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we propose that a new strategy to screen small-molecule antagonists blocking SARS-CoV-2 membrane fusion. Using cell membrane chromatography (CMC), we found that ha...

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Detalles Bibliográficos
Autores principales: Hu, Shiling, Wang, Nan, Chen, Shaohong, Zhang, Huajun, Wang, Cheng, Ma, Weina, Zhang, Xinghai, Wu, Yan, Lv, Yanni, Xue, Zhuoyin, Bai, Haoyun, Ge, Shuai, He, Huaizhen, Lu, Wen, Zhang, Tao, Ding, Yuanyuan, Liu, Rui, Han, Shengli, Zhan, Yingzhuan, Zhan, Guanqun, Guo, Zengjun, Zhang, Yongjing, Lu, Jiayu, Gao, Jiapan, Jia, Qianqian, Wang, Yuejin, Wang, Hongliang, Lu, Shemin, Jin, Tengchuan, Chiu, Sandra, He, Langchong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195862/
https://www.ncbi.nlm.nih.gov/pubmed/37211174
http://dx.doi.org/10.1016/j.bcp.2023.115617

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