Refined high-content imaging-based phenotypic drug screening in zebrafish xenografts

Zebrafish xenotransplantation models are increasingly applied for phenotypic drug screening to identify small compounds for precision oncology. Larval zebrafish xenografts offer the opportunity to perform drug screens at high-throughput in a complex in vivo environment. However, the full potential o...

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Detalles Bibliográficos
Autores principales: Sturtzel, C., Grissenberger, S., Bozatzi, P., Scheuringer, E., Wenninger-Weinzierl, A., Zajec, Z., Dernovšek, J., Pascoal, S., Gehl, V., Kutsch, A., Granig, A., Rifatbegovic, F., Carre, M., Lang, A., Valtingojer, I., Moll, J., Lötsch, D., Erhart, F., Widhalm, G., Surdez, D., Delattre, O., André, N., Stampfl, J., Tomašič, T., Taschner-Mandl, S., Distel, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195872/
https://www.ncbi.nlm.nih.gov/pubmed/37202469
http://dx.doi.org/10.1038/s41698-023-00386-9

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