Cargando…

Basic and clinical study of efficacy and adverse effects of flumatinib in Ph(+) ALL

Objective: To investigate the efficacy and safety of chemotherapy in treating Ph+ ALL based on flumatinib. Methods: The clinical data of 29 patients with Ph+ ALL receiving flumatinib-based chemotherapy in Sichuan Provincial People’s Hospital from January 2020 to January 2023 were collected for analy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jun, Wu, Jiafei, Wang, Yijing, Zheng, Boyue, Wang, Yu, Jiang, Chuanyan, Zou, Mengying, Li, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196016/ https://www.ncbi.nlm.nih.gov/pubmed/37214433 http://dx.doi.org/10.3389/fphar.2023.1178393

Ejemplares similares

Studies on the inhibitory effect of isavuconazole on flumatinib metabolism in vitro and in vivo
por: Liu, Ya-nan, et al.
Publicado: (2023)

Pharmacokinetics of single- and multiple-dose flumatinib in patients with chronic phase chronic myeloid leukemia
por: Jiang, Bo, et al.
Publicado: (2023)

PB1749: APOPTOTIC EFFECT OF FLUMATINIB COMBINED WITH BCL2 INHIBITOR ON PH+ B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
por: Gu, Y., et al.
Publicado: (2022)

Effect of high-fat diet on the pharmacokinetics and safety of flumatinib in healthy Chinese subjects
por: Kuang, Yun, et al.
Publicado: (2020)

P363: A PHASE II STUDY OF FLUMATINIB WITH CHEMOTHERAPY FOR NEWLY DIAGNOSED PH/BCR-ABL1-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA IN ADULTS: UPDATED RESULTS FROM RJ-ALL2020.2A TRIAL
por: Liu, Weiyang, et al.
Publicado: (2023)

Flumatinib plus venetoclax as an effective therapy for Philadelphia chromosome‐positive acute myeloid leukemia: A case report
por: Huang, Si‐Man, et al.
Publicado: (2023)

Efficacy of Ceftazidime-Avibactam Versus Polymyxin B and Risk Factors Affecting Clinical Outcomes in Patients With Carbapenem-Resistant Klebsiella pneumoniae Infections a Retrospective Study
por: Fang, Jie, et al.
Publicado: (2021)

The Efficacy and Safety of Pulmonary Vasodilators in Pediatric Pulmonary Hypertension (PH): A Systematic Review and Meta-analysis
por: Shu, Tingting, et al.
Publicado: (2021)

Basic research investment, innovation capability improvement, and economic growth efficiency
por: Jiang, Yichen, et al.
Publicado: (2022)

Flumatinib, a selective inhibitor of BCR-ABL/PDGFR/KIT, effectively overcomes drug resistance of certain KIT mutants
por: Zhao, Jie, et al.
Publicado: (2014)

Evaluation of the Direct Costs of Managing Adverse Drug Events in all Ages and of Avoidable Adverse Drug Events in Older Adults in Japan
por: Katsuno, Hayato, et al.
Publicado: (2021)

Adverse events associated with molnupiravir: a real-world disproportionality analysis in food and drug administration adverse event reporting system
por: Liang, Yankun, et al.
Publicado: (2023)

A Smart pH-Sensitive Delivery System for Enhanced Anticancer Efficacy via Paclitaxel Endosomal Escape
por: Yang, Yihua, et al.
Publicado: (2019)

Editorial: Herbal Medicines in Managing Stroke and Neurodegenerative Diseases—Is There Evidence Based on Basic and Clinical Studies?
por: Xu, Haiyu, et al.
Publicado: (2021)

pH Responsive Polymer Micelles Enhances Inhibitory Efficacy on Metastasis of Murine Breast Cancer Cells
por: Wang, Jie, et al.
Publicado: (2018)

Current Status of Septic Cardiomyopathy: Basic Science and Clinical Progress
por: Lin, Huan, et al.
Publicado: (2020)

Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels
por: Fan, Fenling, et al.
Publicado: (2021)

Drug-induced tooth discoloration: An analysis of the US food and drug administration adverse event reporting system
por: Wang, Jun, et al.
Publicado: (2023)

Editorial: Herbal medicines in managing stroke and neurodegenerative diseases—Is there evidence based on basic and clinical studies?, volume II
por: Liang, Huazheng, et al.
Publicado: (2022)

Efficacy of polyethylene glycol loxenatide versus insulin glargine on glycemic control in patients with type 2 diabetes: a randomized, open-label, parallel-group trial
por: Zhang, Shuo, et al.
Publicado: (2023)

Efficacy of lenvatinib combined with sequential transarterial chemoembolization for primary hepatocellular carcinoma and the effects on serum basic fibroblast growth factor and vascular endothelial growth factor
por: Xie, Qing-Yun, et al.
Publicado: (2022)

Synergistic Activity of Capsaicin and Colistin Against Colistin-Resistant Acinetobacter baumannii: In Vitro/Vivo Efficacy and Mode of Action
por: Guo, Tingting, et al.
Publicado: (2021)

Efficacy and Adverse Events of PD-1 Inhibitors in Patients With Advanced Urothelial Carcinoma From a Real-World Experience
por: Sun, Fengze, et al.
Publicado: (2022)

Hyperuricaemia, gout and related adverse events associated with antihypertensive drugs: A real-world analysis using the FDA adverse event reporting system
por: Jiao, Xue-Feng, et al.
Publicado: (2023)

Editorial: Sepsis: Basic, Clinical and Therapeutic Approaches
por: Kang, Yan, et al.
Publicado: (2022)

Xin Su Ning—A Review of Basic and Clinical Pharmacology Integrated With Traditional Chinese Medicine Antiarrhythmic Theory
por: Wang, Xuan, et al.
Publicado: (2021)

PB1707: COMBINATION OF AZACITIDINE AND FLUMATINIB INDUCES APOPTOSIS IN SUP-B15 CELLS BY BLOCKING THE CELL CYCLE THROUGH THE MDM2-P53 SIGNALING PATHWAY
por: Zhang, Linyao, et al.
Publicado: (2023)

cGAS-STING Signaling Pathway and Liver Disease: From Basic Research to Clinical Practice
por: Chen, Bangjie, et al.
Publicado: (2021)

Traditional Chinese Medicine in Treating Influenza: From Basic Science to Clinical Applications
por: Xiong, Yibai, et al.
Publicado: (2020)

Bring the life stages into the domain of basic and clinical pharmacology
por: Yao, Lan, et al.
Publicado: (2022)

The Therapeutic Efficacy of Danhong Injection Combined With Percutaneous Coronary Intervention in Acute Coronary Syndrome: A Systematic Review and Meta-Analysis
por: Zou, Jun-Bo, et al.
Publicado: (2018)

Retraction: pH responsive polymer micelles enhances inhibitory efficacy on metastasis of murine breast cancer cells
por: Frontiers Editorial Office
Publicado: (2023)

The efficacy and adverse events of delafloxacin in the treatment of acute bacterial infections: A systematic review and meta-analysis of randomized controlled trials
por: He, Rong, et al.
Publicado: (2022)

Hurdles in Basic Science Translation
por: Perry, Christina J., et al.
Publicado: (2017)

Impact of the CYP2D6 Genotype on Metoprolol Tolerance and Adverse Events in Elderly Chinese Patients With Cardiovascular Diseases
por: Chen, Jianqiao, et al.
Publicado: (2022)

Neurological Adverse Events Associated With Esketamine: A Disproportionality Analysis for Signal Detection Leveraging the FDA Adverse Event Reporting System
por: Guo, Haoning, et al.
Publicado: (2022)

The Use of Oseltamivir as Adjunctive Therapy for the Treatment of Hand-Food-and-Mouth Disease: A Meta-Analysis of Randomized Clinical Trials
por: Zhao, Yijing, et al.
Publicado: (2021)

Case report: A relatively rare adverse event caused by carbetocin— placenta interception
por: Li, Jun-Qiang, et al.
Publicado: (2023)

Corrigendum: Neurological adverse events associated with esketamine: A disproportionality analysis for signal detection leveraging the FDA adverse event reporting system
por: Guo, Haoning, et al.
Publicado: (2022)

Efficacy and Safety of Finerenone in Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
por: Zhang, Ming-Zhu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9h7ci6o79ipbpk1navs5dvujse