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Cell-penetrating TLR inhibitor peptide alleviates ulcerative colitis by the functional modulation of macrophages

Toll-like receptors (TLRs) have a crucial role not only in triggering innate responses against microbes but in orchestrating an appropriate adaptive immunity. However, deregulated activation of TLR signaling leads to chronic inflammatory conditions such as inflammatory bowel disease (IBD). In this s...

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Detalles Bibliográficos
Autores principales: Thapa, Bikash, Pak, Seongwon, Chung, Dohyeon, Shin, Hye Kyoung, Lee, Seong Ho, Lee, Keunwook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196052/
https://www.ncbi.nlm.nih.gov/pubmed/37215126
http://dx.doi.org/10.3389/fimmu.2023.1165667