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Assessment of precision in growth inhibition assay (GIA) using human anti-PfRH5 antibodies

BACKGROUND: For blood-stage malaria vaccine development, the in vitro growth inhibition assay (GIA) has been widely used to evaluate functionality of vaccine-induced antibodies (Ab), and Plasmodium falciparum reticulocyte-binding protein homolog 5 (RH5) is a leading blood-stage antigen. However, pre...

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Detalles Bibliográficos
Autores principales: Miura, Kazutoyo, Diouf, Ababacar, Fay, Michael P., Barrett, Jordan R., Payne, Ruth O., Olotu, Ally I., Minassian, Angela M., Silk, Sarah E., Draper, Simon J., Long, Carole A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196285/
https://www.ncbi.nlm.nih.gov/pubmed/37208733
http://dx.doi.org/10.1186/s12936-023-04591-6