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Conformational analysis and interaction of the Staphylococcus aureus transmembrane peptidase AgrB with its AgrD propeptide substrate

Virulence gene expression in the human pathogen, S. aureus is regulated by the agr (accessory gene regulator) quorum sensing (QS) system which is conserved in diverse Gram-positive bacteria. The agr QS signal molecule is an autoinducing peptide (AIP) generated via the initial processing of the AgrD...

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Detalles Bibliográficos
Autores principales: Bardelang, Philip, Murray, Ewan J., Blower, Isobel, Zandomeneghi, Sara, Goode, Alice, Hussain, Rohanah, Kumari, Divya, Siligardi, Giuliano, Inoue, Katsuaki, Luckett, Jeni, Doutch, James, Emsley, Jonas, Chan, Weng C., Hill, Philip, Williams, Paul, Bonev, Boyan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196373/
https://www.ncbi.nlm.nih.gov/pubmed/37214482
http://dx.doi.org/10.3389/fchem.2023.1113885