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Biased computation of probability of target attainment for antimicrobial drugs

The medical literature is replete with articles in which there is confusion between “free concentration” and “unbound fraction” (f (u)), which is the ratio of free to total plasma concentration. The lack of clarity in distinguishing between these two terms has led to biased computations, erroneous i...

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Detalles Bibliográficos
Autores principales: Toutain, Pierre‐Louis, Gandia, Peggy, Pelligand, Ludovic, Ferran, Aude A., Lees, Peter, Bousquet‐Mélou, Alain, Concordet, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196429/
https://www.ncbi.nlm.nih.gov/pubmed/37025064
http://dx.doi.org/10.1002/psp4.12929

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