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PBPK modeling of ivermectin—Considerations for the purpose of developing alternative routes to optimize its safety profile
Although single‐dose ivermectin has been widely used in mass‐drug administration programs for onchocerciasis and lymphatic filariasis for many years, ivermectin may have utility as an endectocide with mosquito‐lethal effects at dosages greater and longer than those used to treat helminths. The final...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196439/ https://www.ncbi.nlm.nih.gov/pubmed/36840414 http://dx.doi.org/10.1002/psp4.12950 |